Browsing by Subject "Biological organs"

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  • Biodistribution, biocompatibility and targeted accumulation of magnetic nanoporous silica nanoparticles as drug carrier in orthopedics 
    Janßen, Hilke Catherina; Angrisani, Nina; Kalies, Stefan; Hansmann, Florian; Kietzmann, Manfred; Warwas, Dawid Peter; Behrens, Peter; Reifenrath, Janin (London : BioMed Central Ltd., 2020)
    Background: In orthopedics, the treatment of implant-associated infections represents a high challenge. Especially, potent antibacterial effects at implant surfaces can only be achieved by the use of high doses of antibiotics, ...
  • Phenotypic drug screening in a human fibrosis model identified a novel class of antifibrotic therapeutics 
    Gerckens, Michael; Schorpp, Kenji; Pelizza, Francesco; Wögrath, Melanie; Reichau, Kora; Ma, Huilong; Dworsky, Armando-Marco; Sengupta, Arunima; Stoleriu, Mircea Gabriel; Heinzelmann, Katharina; Merl-Pham, Juliane; Irmler, Martin; Alsafadi, Hani N.; Trenkenschuh, Eduard; Sarnova, Lenka; Jirouskova, Marketa; Frieß, Wolfgang; Hauck, Stefanie M.; Beckers, Johannes; Kneidinger, Nikolaus; Behr, Jürgen; Hilgendorff, Anne; Hadian, Kamyar; Lindner, Michael; Königshoff, Melanie; Eickelberg, Oliver; Gregor, Martin; Plettenburg, Oliver; Yildirim, Ali Önder; Burgstaller, Gerald (Washington, DC [u.a.] : Assoc., 2021)
    Fibrogenic processes instigate fatal chronic diseases leading to organ failure and death. Underlying biological processes involve induced massive deposition of extracellular matrix (ECM) by aberrant fibroblasts. We subjected ...